Building a CAR-Treg: Going from the basic to the luxury model

Cellular Immunology（2020）

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摘要

•Advances in use of chimeric antigen receptors (CARs) in Tregs are reviewed.•Factors to consider when creating CAR-Tregs are discussed.•How progress in CAR-T cell design can be applied to Tregs is discussed.

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关键词

Chimeric Antigen Receptor,Regulatory T cells,Tolerance,Transplantation,Autoimmunity,Signaling

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