Effect of acetylsalicylic acid on inflamed adipose tissue. Insulin resistance and hepatic steatosis in a mouse model of diet-induced obesity

•Acetylsalicylic acid can counteract the inflammatory process induced by high-fat diet consumption•Acetylsalicylic acid acts on adipose tissue reducing the release of inflammatory cytokines•Acetylsalicylic acid can revert high insulin and glucose levels induced by high-fat diet•Acetylsalicylic acid improves hepatic steatosis by a mechanism not involving the resolution of inflammation in liver