The efficacy of teriparatide on lumbar spine bone mineral density, vertebral fracture incidence and pain in post-menopausal osteoporotic patients: A systematic review and meta-analysis

•Teriparatide (20 μg/day) significantly improves lumbar spine bone mineral density.•Teriparatide (20 μg/day) reduces vertebral fracture incidence and pain.•Increased teriparatide dose (40 μg/day) may have even greater clinical efficacy.•Further investigation on safety profiles for longer-term treatment is warranted.