Enhanced post-licensure safety surveillance of a new recombinant acellular pertussis vaccine licensed as a monovalent (aP, Pertagen®) and tetanus, reduced-dose diphtheria combination (TdaP, Boostagen®) vaccine for immunization of adolescents and adults in Thailand

Librada Fortuna,Surasith Chaithongwongwatthana,Ngamphol Soonthornworasiri,Jane Spiegel,Wassana Wijagkanalan,Souad Mansouri,Anita H.J. van den Biggelaar,Hong Thai Pham

VACCINE（2020）

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摘要

•Pharmacovigilance confirms the safety of recombinant pertussis vaccine post-licensure.•Genetically detoxified pertussis vaccine is well-tolerated by adolescents and adults.•Recombinant aP and its TdaP combination can be used safely in pregnant women.

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关键词

Safety, Post-licensure, Pharmacovigilance, Pertussis, Booster, Recombinant, Pregnancy

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