MP01-20 TLR7/8-AGONIST-LOADED M1-MACROPHAGE-DERIVED NANOVESICLES PROMOTE THE POLARIZATION OF MACROPHAGES TO ENHANCE BLADDER CANCER IMMUNOTHERAPY

INTRODUCTION AND OBJECTIVE:Tumor-associated macrophages (TAM) are abundant in many cancers including bladder cancer, and often display an immune-suppressive M2-like phenotype to fosters tumor growt...