双调蛋白及其在气道炎性疾病中作用的研究进展

Lin chuang er bi yan hou tou jing wai ke za zhi = Journal of clinical otorhinolaryngology, head, and neck surgery（2018）

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摘要

Amphiregulin is a member of epidermal growth factor family,and is also one of the ligand of epidermal growth factor receptor,it participates in many physiological and pathological process by combining with EGFR.Researches have proved that AREG participates in asthma and airway inflammatory diseases caused by smoking and PM 2.5,and AREG plays an important role in the process of airway remodeling and inflammation.This paper mainly reviews the expression and function of AREG,and focus on it's research status in airway inflammatory disease.

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epidermal growth factor receptor,airway inflammation,amphiregulin,asthma

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