Synthesis of 2-imidazolines by co-grinding of N-tosylaziridines and nitriles

Aramita De,Sougata Santra,Igor S. Kovalev,Dmitry S. Kopchuk,Grigory V. Zyryanov,Oleg N. Chupakhin,Valery N. Charushin,Adinath Majee

Mendeleev Communications（2020）

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摘要

Solvent-free solid-state co-grinding of N-tosylaziridines and nitriles in the presence of perchloric acid as the catalyst affords 2-imidazolines in good yields.

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关键词

solvent-free reactions,aziridines,grinding,2-imidazolines,nitriles,heterocyclization

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