Polyarteritis nodosa with genital necrosis

Polyarteritis nodosa (PAN) is a multisystemic disease that is characterized by the presence of necrotizing vasculitis of small and medium-sized blood vessels. Genital compromise is rare. Our patient presented a systemic disease associated to genital signs (penis and scrotum skin necrosis). A bilateral testicular and glans biopsy was performed and with PAN diagnosis, immunosuppressives treatment was realised for 6 weeks, with favorable progress.