P1725USAGE AND OUTCOMES FOR EXPANDED CRITERIA DONOR KIDNEY TRANSPLANTATION IN THE KOREA CHARACTERIZED BY KIDNEY DONOR PROFILE INDEX, SINGLE CENTER STUDY

Abstract Background and Aims The demand for Kidney transplantation (KT) is increasing and the number of patients who are waiting for KT is steadily increasing. Therefore, there is an increasing prevalence of KT done by cadaver donor especially, expanded criteria donor. We used Kidney Donor Profile Index (KDPI) to predict the renal prognosis of expanded criteria donor (ECD) KT recipient. Method We investigated patients undergo KT by ECD from March 2013 to June 2018 respectively. Through the donor’s last creatinine level, KDPI score, and Kidney Donor Risk Index (KDRI) score the renal survival rate was compared with ROC curve analysis. Results The mean age of a total 59 ECD KT recipient is 53.85 ± 9.9 years old. Mean follow up duration after KT was 35.0 ± 18.5 months. 10 patients had KDPI score above 85 (KDPI ≥ 85). Five cases undergo dialysis after KT. Nine cases expired during follow up (four sepsis, three sudden cardiac arrest, one hyperkalemia). Glomerular filtration rate one year after KT was significantly associated with KDPI (r=-0.772, p<0.001). The area under curve (AUC) of KDPI was 0.700 (95% CI 0.494-0.906) and cut off point was 75.5. All renal survival patients had KDPI score below 75.5 Conclusion Our results show that KDPI could be used as an indicator for predicting the prognosis of the Korean ECD KT.