Synthesis of Two Novel Mixed Bifunctional Chelating Agents: DO2AP(tBu)4 and DO3AP(tBu)4

Luciano Lattuada,Giovanni B. Giovenzana,Fabio Travagin, Luca Biondi

Synlett（2020）

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摘要

A convenient synthesis of two novel macrocyclic bifunctional chelating agents (BFCAs), formally derived from the well-known ligands DO3A and DOTA by selective replacement of one carboxymethyl side arm with a phosphonomethyl residue, is reported.

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关键词

bifunctional chelating agents,DO3A,DOTA,phosphonic group,protecting group

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