SAXS studies of X-ray induced disulfide bond damage: Engineering high-resolution insight from a low-resolution technique

Timothy R Stachowski
Timothy R Stachowski
Mary E Snell
Mary E Snell

PloS one, 2020.

Cited by: 0|Views3
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Abstract:

A significant problem in biological X-ray crystallography is the radiation chemistry caused by the incident X-ray beam. This produces both global and site-specific damage. Site specific damage can misdirect the biological interpretation of the structural models produced. Cryo-cooling crystals has been successful in mitigating damage but n...More

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