Relation of cartonectin (CTRP3) and dyslipedimia in adolescent type 1 diabetic patient

To evaluate cartonectin (CTRP3) levels in adolescents type 1 diabetic patient. It is a cross sectional study, including 56 type 1 diabetic patients and 18 age and sex matched control group. Blood samples were taken for assessment of liver and kidney function, glycosylated hemoglobin (HbA1c), lipid profile and Serum cartonectin by ELISA. Urine samples were taken for assessment of albumin/creatinine ratio. Diabetic patients had a significantly higher diastolic blood pressure, lipid profile and cartonectin. Cartonectin had a significant negative correlation with waist/hip ratio, total cholesterol/HDL and triglyceride/HDL and negative correlation with HDL.CTRP3 increase in Egyptian adolescents with type 1DM, and showed significant correlation with lipoproteins risk ratios as total cholesterol/HDL and triglyceride/HDL, so it may act as biomarker of dyslipedimia in type 1DM.