Environmental pharmaceuticals and climate change: The case study of carbamazepine in M. galloprovincialis under ocean acidification scenario

Marica Mezzelani,Alessandro Nardi,Ilaria Bernardini,Massimo Milan,Luca Peruzza,Giuseppe d'Errico,Daniele Fattorini,Stefania Gorbi,Tomaso Patarnello,Francesco Regoli

Environment International（2021）

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摘要

•Combined effects of carbamazepine and reduced pH were investigated in M. galloprovincialis.•Hypercapnia had a limited influence on carbamazepine accumulation.•Interactive effects were observed at both transcriptional and cellular level.•Immune system, cellular homeostasis and oxidative processes were mostly affected.•Weighted elaboration of results revealed higher hazard by multiple stressors.

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关键词

Multiple stressors,Pharmaceuticals,Ocean acidification,Gene expression,Cellular alteration/toxicity,Risk assessment,Mytilus galloprovincialis

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