Simulation of Single Bio Particles in XFEL Coherent Diffraction Master Curve for Photon Counts Estimation

To image biological objects using coherent X-ray diffraction (CXDI), the resolution limitation is mainly resulted from insufficient photon flux at current XFEL facilities. In this report, a photon-flux master curve of particle detection is generated from single shot computer simulation of different biological particles in Protein Data Bank and EMDataBank. The master curve can be applied to estimate scatted X-ray intensity and guide the design of CXDI experiments.