Optimization of single dose post-operative nefopam therapy in the elderly on the basis of pharmacokinetics and pharmacodynamics

Z. Djerada, A. Fournet-Fayard, C. Feliu, C. Lelarge, C. Gozalo,H. Millart,J. M. Malinovsky

FUNDAMENTAL & CLINICAL PHARMACOLOGY（2014）

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analgesia,elderly,exposure-response,logistic regression,nefopam,population pharmacokinetics,renal impairment

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