Synthesis and Crystal Structure of (2E,6E)-2,6-bis(2,3-dimethoxybenzylidene)cyclohexanone

The new title compound (2E,6E)-2,6-bis(2,3-dimethoxybenzylidene)cyclohexanone (C(24)H(26)O(5), M(r) = 394.45) has been synthesized, and its crystal structure was studied. The title compound crystallizes in the orthorhombic system, space. group Pca2(1) with a = 17.536(2), b = 14.8515(16), c = 8.0512(9) angstrom, V = 2096.8(4) angstrom(3), Z= 4, D(c) = 1.250 g/cm(3), lambda = 0.71073 angstrom, mu = 0.087 mm(-1) and F(000) = 840. The structure was solved by direct methods and refined to R = 0.0533 and wR = 0.1248 from 2727 observed reflections (I > 2 sigma(I)). The title molecules are connected through hydrogen bonds to generate a 3-D supramolecule. The preliminary biological tests showed definitely biological activity for the title compound.