Reversal of TSPO Upregulation in the Diabetic Heart by Chronic TSPO Gene Silencing Causes Metabolic Sink via an Increase in ROMK Expression

Zeki Ilkan,Benjamin Strauss,Fadi G. Akar

CIRCULATION（2018）

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摘要

Introduction: The mitochondrial translocator protein (TSPO) is an integral component of a macromolecular complex that regulates cell death \u0026 survival pathways. Myocardial TSPO levels are markedly i...

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关键词

Arrhythmia mapping,Diabetes Mellitus,Gene therapy,Ion channels,Ischemia reperfusion

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