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Acute Post-ischemic GPER1 Activation Protects the Myocardium Against Ischemia/Reperfusion Injury by Reducing Mitochondrial Protein Ubiquitination, Histone Acetylation and Calpain10 levels and Inhibition of the mPTP Opening

Yansheng Feng,Mohammad E. Kabir, Cesar Humberto Hernandez,Bjorn Olde,Fredrik Leeb-Lundberg,Jean C. Bopassa

CIRCULATION（2015）

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Abstract
Introduction: We recently found that acute pre-ischemic estrogen-induced cardioprotection against ischemia/reperfusion injury was mainly mediated via G protein-coupled estrogen receptor1 (GPER1) ac...
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Key words
Cardioprotection,Estrogen,GPER1,Signaling,Ischemia/reperfusion
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