Population Pharmacokinetics of Nivolumab in Japanese Patients with Nonsmall Cell Lung Cancer.

Makiko Tohi,Kei Irie,Tomoyuki Mizuno, Hiroyuki Okuyoshi,Masaki Hirabatake,Hiroaki Ikesue,Nobuyuki Muroi,Masaaki Eto,Shoji Fukushima,Keisuke Tomii,Tohru Hashida

CLINICAL PHARMACOLOGY & THERAPEUTICS（2023）

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摘要

A real-world nivolumab population PK model was developed using an opportunistic sampling strategy in Japanese patients with NSCLC. Further studies are warranted to characterize the exposure-response relationship and determine the optimal dosing regimens for these patients.

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关键词

nivolumab,population pharmacokinetics,real-world data,nonsmall cell lung cancer

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