Cerebrovascular autoregulation impairments during cardiac surgery with cardiopulmonary bypass are associated with postoperative cognitive deterioration

Post-operative cognitive dysfunction (POCD) occurs in 33–83% of patients after cardiac surgery with cardiopulmonary bypass (CPB). Intraoperative non-invasive monitoring of cerebrovascular autoregulation (CA) of individual patient may help to prevent POCD by detecting and control of optimal mean arterial blood pressure (optABP) or optimal cerebral perfusion pressure (optCPP). Objectives of the study are to investigate the association between CA dynamics and POCD.