[The Correlation of Minimal Residual Disease with Prognosis in TCF3-PBX1+ Acute Lymphoblastic Leukemia in Children].

Zhongguo shi yan xue ye xue za zhi(2020)

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摘要
OBJECTIVE:To investigate the consistency between FCM and PCR on the detecting of MRD in TCF3-PBX1 +METHODS:55 cases of paediatric TCF3-PBX1 +RESULTS:Among the 55 children with TCF3-PBX1 ++--+--CONCLUSION:The detection result of MRD in TCF3-PBX1 detect by FCM and PCR shows better consistency. MRD positivity detected by FCM at the end of induction therapy (day 33) predicts a high risk of relapse in TCF3-PBX1 ALL patients.
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关键词
acute lymphoblastic leukemia,minimal residual disease,prognosis
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