Relationship between Metabolic Toxicity and Efficacy of Everolimus in Patients with Neuroendocrine Tumors (NETs): A Pooled Analysis from the Randomized, Phase 3 RADIANT-3 and RADIANT-4 Trials

Nicola Fazio,Carlo Carnaghi,Roberto Buzzoni,Juan W Valle,Fabian Herbst,Antonia Ridolfi,Jonathan Strosberg,Matthew H Kulke,Marianne E Pavel,James C Yao

NEUROENDOCRINOLOGY（2018）

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摘要

Although limitations apply because of the small number of AEs observed, there was no significant impact of these AEs on PFS; this suggests similar efficacy in the presence or absence of these events.

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关键词

adverse events,everolimus,radiant-3,radiant-4,landmark analysis,mtor inhibitors,targeted therapy,neuroendocrine tumors

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