Accessing Tri-substituted gamma-Lactam Scaffolds Via Cascade Reactions: What Opportunities For Libraries!

Karine Bonnet,Mads H. Clausen,Nicolas Fleury-Bregeot, Claude Lardy,Remy Morgentin,Thomas E. Nielsen,Michael Axman Petersen, Martin Ohsten Rasmussen,Didier Roche, Peng Wu

FASEB JOURNAL（2016）

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摘要

The European Lead Factory is an EU-based initiative (part of the Innovative Medicines Initiative), which has been set to foster drug discovery in Europe. Among the objectives, a 200,000-compound co...

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