Breaths, Twists, and Turns of Atomistic Nucleosomes

•Atomistic molecular dynamics simulations represent powerful tools to study nucleosome dynamics.•Atomistic simulations can reveal nucleosome breathing, twisting, unwrapping.•Atomistic simulations can reveal the impact of histone modifications and variants on nucleosome dynamics.•Atomistic simulations can reveal the structure and dynamics of nucleosomes in complexes with interacting partners.