In-vitro Cholesterol Reducing Property of Human Gut Bacteria from Rourkela Population, Odisha, India

Probiotic bacteria are reported to reduce cholesterol by different mechanisms and hence can be utilized to reduce the blood cholesterol level of hypercholesterolemic patients. Probiotic bacteria must be population specific to be used in particular population. Bacteria isolated from faeces of healthy volunteers from Rourkela, Odisha, India were screened for their cholesterol reducing property in MRS broth for 72 hours. Results showed that cholesterol reducing property was increased with time of incubation and there was no increase in cholesterol reduction potential of the gut isolates in presence of 0.05% bile salt in media. Three isolates MS1, MS4 and MS7 were most potent in reducing cholesterol according to our present study. These isolates could emerge as population specific probiotics after further studies.