Germline mutations in BAP1 predispose to melanocytic tumors

PIGMENT CELL & MELANOMA RESEARCH(2011)

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摘要
Thomas Wiesner and colleagues report that germline mutations in BAP1 predispose to melanocytic tumors ranging histopathologically from epithelioid nevi to atypical melanocytic proliferations. Some BAP1 mutation carriers also developed uveal or cutaneous melanomas.
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