The Interleukin-1 Balance During Encephalitis Is Associated With Clinical Severity, Blood-Brain Barrier Permeability, Neuroimaging Changes, and Disease Outcome

Benedict Daniel Michael,Michael J. Griffiths,Julia Granerod,David Brown,Geoff Keir, Gosia Wnęk,Daniel J. Cox,Rishma Vidyasagar,Ray Borrow,Laura M. Parkes,Tom Solomon

user-5bd69975530c70d56f390249（2016）

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摘要

Encephalitis is parenchymal brain inflammation, commonly due to herpes simplex virus (HSV). Key host inflammatory mediators and their relationship to blood-brain barrier (BBB) permeability, neuroimaging changes, and disease outcome are poorly understood.

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关键词

Encephalitis,Blood–brain barrier,Vascular permeability,Interleukin,Inflammation,Herpes simplex virus,Cerebrospinal fluid,Interleukin 10,Immunology,Pathology,Medicine

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