Gene-Environment Interaction between Arg72Pro SNP and Selected Environmental Exposures among Brazilian Women Diagnosed with Benign Breast Disease.

Rafaela Soares Senra Da Costa,Rosalina Jorge Koifman, Viviane Ferreira Esteves, Marla Presa Raulino Schilling,Sergio Koifman,Ilce Ferreira Da Silva

Asian Pacific journal of cancer prevention : APJCP（2020）

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摘要

The Arg/Pro genotype was the most frequent in the BBD cohort. When compared with the Arg/Arg genotype, the presence of Arg/Pro genotype and solvents, fabric and cleaning products exposure increased the risk of BBD. When compared with Pro/Pro genotype, there were interactions between recessive model with alcohol consumption and exposure to hair products on the risk of BBD.

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关键词

Benign Breast Disease,Epidemiology,public health

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