Previous Dengue Infection and Mortality in Coronavirus Disease 2019 (COVID-19)

Odilson M. Silvestre, Leticia R. Costa, Bianca V. R. Lopes,Mariana R. Barbosa, Karenn K. P. Botelho, Kelvyn L. C. Albuquerque,Anna G. S. Souza, Lorran A. Coelho, Anderson J. de Oliveira,Cinthia B. Barantini,Sebastiao A. V. M. Neves,Wilson Nadruz,James H. Maguire,Miguel M. Fernandes-Silva

Clinical infectious diseases/Clinical infectious diseases (Online University of Chicago Press)（2020）

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摘要

We studied 2351 participants with coronavirus disease 2019; 1177 (50%) reported previous dengue infection. Those without previous dengue had a higher risk of death (hazard ratio: .44; 95% confidence interval: .22-.89; P = .023) in 60-day follow-up. These findings raise the possibility that dengue might induce immunological protection against severe acute respiratory syndrome coronavirus 2.

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COVID-19,dengue,mortality

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