Investigating the EPR effect of nanomedicines in human renal tumors via ex vivo perfusion strategy

Nano Today(2020)

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摘要
The EPR effect of 41 renal tumors collected from clinical patients were analyzed via perfusion strategy, correlating the EPR effect in human tumors with that in animal models and confirming that more than 87 % of the examined renal tumors possess the considerable EPR effect, which yet showed significant diversity and heterogeneity in different patients.
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关键词
EPR effect,Ex vivo perfusion,Anticancer nanomedicine,X-ray computed tomography,Cancer therapy
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