Convenient One-Step Synthesis Of Quinoline-3,4-Dicarboxylate Derivatives

SYNTHETIC COMMUNICATIONS（2021）

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摘要

Herein a practical and convenient procedure for the one-step synthesis of quinoline-3,4-dicarboxylate derivatives from isatins and beta-keto esters in alcohols by sulfuric acid-catalyzed was described. This novel protocol offers the advantages of high conversion rates, short reaction times, and easy handling.[GRAPHICS].

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关键词

Isatins, beta-keto esters, quinoline-3, 4-dicarboxylate derivatives, sulfuric acid

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