Children With Sleep-Related Issues Have Lower Life Satisfaction And Higher Physical Stress Experience

SESSION TITLE: New Insights Into the Relationship Between OSA and Cardiovascular Disease SESSION TYPE: Original Investigations PRESENTED ON: October 18-21, 2020 PURPOSE: To identify problems with health-related quality of life (HR-QoL) in children with sleep disturbance. METHODS: Patients ages 5-17 years visiting sleep laboratory from 09/2019 to 01/2020 for overnight PSG participated in the study. Control participants were seen in general pediatrics during 02/2020 for issues other than sleep disturbance. HR-QoL was assessed by PROMIS questionnaires. Statistical analysis was conducted using R 3.6.0. RESULTS: 122 patients were studied: 70 males (57.4%). Thirty one (25.4%) had mild OSA, 12 (9.8%) moderate OSA, 19 (15.6%) severe OSA, 37 (30.3%) were without OSA and 23 (18.9%) were controls. Severity of OSA was not correlated with any HR-QoL domain. Patients visiting the sleep laboratory had lower life satisfaction (p=0.05) and higher physical stress experience (p=0.005). Age, BMI were negatively and N3 sleep was positively associated with family relations (p<0.001, 0.03, 0.006, respectively). N3 sleep was positively and age was negatively associated with life satisfaction (p<0.001, p=0.003, respectively). Increase in arousals was associated with increased physical stress experience (p=0.03). N3 sleep and anger were negatively associated with each other (p=0.05). Significant correlations between several PROMIS domains were also observed. CONCLUSIONS: Children with OSA have problems with physical stress and with life satisfaction. Deep sleep was associated with problems with family relations and anger. Regression analysis suggested that age was negatively associated with family relations and life satisfaction. CLINICAL IMPLICATIONS: Knowledge of associations between sleep disturbance and specific HR-QoL domains will identify the most appropriate and effective intervention in children. DISCLOSURES: No relevant relationships by Amanda Beneat, source=Web Response No relevant relationships by BHARAT BHUSHAN, source=Web Response No relevant relationships by Douglas Johnston, source=Web Response No relevant relationships by John Maddalozzo, source=Web Response No relevant relationships by Michael Miller, source=Web Response No relevant relationships by Dana Thompson, source=Web Response No relevant relationships by Sujay Turakhia, source=Web Response No relevant relationships by Sarah Xu, source=Web Response