Application Of Thrombomodulin-Thrombin Generation To Diverse Abnormalities Of The Protein C System
BLOOD(2020)
摘要
Background: Increased thrombin generation is an interesting candidate as a potential indicator of hypercoagulability and thrombosis risk. Increased thrombin generation using the calibrated automated thrombogram (CAT) has been reported in antithrombin deficiency but the CAT does not reflect protein C deficiency without the addition of thrombomodulin (TM). TM activates protein C (PC) in the CAT and reduces thrombin generation.
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关键词
protein,diverse abnormalities,thrombomodulin-thrombin
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