Palbociclib in combination with chemotherapy in pediatric and young adult patients with relapsed/refractory acute lymphoblastic leukemia and lymphoma: A Children's Oncology Group study (AINV18P1).

Elizabeth A Raetz,David T Teachey,Charles Minard,Xiaowei Liu,Robin E Norris,Kristina Z Denic,Joel Reid,Nikki A Evensen,Lia Gore,Elizabeth Fox,Mignon L Loh,Brenda J Weigel,William L Carroll

BLOOD（2023）

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摘要

Palbociclib in combination with re-induction chemotherapy was well tolerated with a RP2D of 50 mg/m /day for 21 days. Complete responses were observed among heavily pretreated patients.

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关键词

acute lymphoblastic leukemia, palbociclib, pediatric, relapse

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