175 the Changing Incident and Case-fatality Rates of Hospitalised Heart Failure in Western Australia Between 2001 and 2016

Incident heart failure (HF) hospitalisation rates in most developed countries are decreasing. However, recent evidence suggests increasing incident rates in younger age groups due to changing risk factors like obesity. We aim to determine the current West Australian (WA) population trends of HF incidence and case-fatality. All WA residents aged 25-94 years, with an incident (first-ever) principal HF discharge diagnosis between 2001 and 2016 were identified. Age- and sex-standardised rate ratios (RR) and 95% confidence intervals (CI) were calculated, stratified by broad age groups, and 5-year eras. Logistic regression identified annual odds ratio (OR) of 30-day mortality and 1-year mortality in 30-day survivors. A total of 22,473 incident HF hospitalisations were identified. HF incidence initially declined but has been increasing since 2006, especially in the younger groups (Table). The OR of 30-day death decreased (0.97, CI 0.96, 0.98, p<.0001) but not at 1 year in 30-day survivors (1.00, CI 0.99, 1.01, p=0.68).TableAnnual % change in age-and sex-standardised HF incident rates with 95% CIs.PeriodAge groups25-5455-7475-9425-94Yr 2001-20053.9 (-2.0,10.1)-4.3 (-7.4,-1.1)-3.4 (-5.6,-0.8)-2.9 (-4.7,-1.1)Yr 2006-20103.4 (-2.0,9.1)4.8(1.6,8.0)0.0 (-2.2,2.3)1.9 (0.1,3.6)Yr 2011-20166.6 (3.2,10.6)3.7 (1.6,5.9)2.1 (0.6,3.6)3.1 (1.9,4.3) Open table in a new tab Hospitalised HF incidence has been rising in WA since 2006 with the greatest growth in younger age groups. The underlying causes require elucidation and coupled with stable 1-year mortality rates, this portends to increasing HF prevalence and resource utilisation for this serious condition.