A Case Of Rosai-Dorfman Disease In An Infant
Annals of Allergy Asthma & Immunology(2020)
摘要
Rosai-Dorfman disease is a rare non-Langerhans cell histiocytosis with an estimated prevalence of 1:200,000. The disease is characterized by an accumulation of activated histiocytes within affected tissues and is most commonly seen in children and young adults. Patients will exhibit bilateral, prominently enlarged, non-tender cervical lymphadenopathy and are often febrile. Lab findings show leukocytosis, polyclonal hypergammaglobulinemia, a hypochromic or normocytic anemia, and elevated ESR. Diagnostic features on pathology are a sinus expansion of large histiocytes.
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关键词
Langerhans Cell Histiocytosis
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