Real-world evidence from a European cohort study of patients with treatment resistant depression: Baseline patient characteristics

K Heerlein,A H Young,C Otte,T Frodl, G Degraeve, W Hagedoorn,A J Oliveira-Maia,V Perez Sola,S Rathod,G Rosso,P Sierra,J Morrens,G Van Dooren, Y Gali,G Perugi

Journal of Affective Disorders（2021）

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摘要

•Real-world evidence was used to assess unmet need in treatment resistant depression•Patients had experienced treatment failure on multiple and wide-ranging treatments•Treatment resistant depression (TRD) was associated with poor quality of life•Patients also had reduced function and productivity, in and outside of work•Treatment resistant depression has a high disease burden and clear unmet treatment need

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关键词

Major depressive disorder,Observational study,Disease burden,Patient-reported outcomes,Health-related quality of life,Socio-economic status

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