Decreased oxidized low-density lipoprotein is associated with improved trunk flexibility in Japanese community-dwelling women

Background/Purpose: Flexibility is one of the components of physical fitness as well as muscle strength that decrease with age. Flexibility has been identified as one of the primary etiologic factors in preventive treatment of musculotendinous strains, and may be triggered by oxidative stress. We investigated whether changes in the oxidative stress marker, malondialdehyde-modified low density lipoprotein (MDA-LDL), is associated with change in trunk flexibility, which is a useful indicator of physical fitness, by a 12 -week exercise administered to Japanese community-dwelling persons. Methods: The present study included 62 women aged 67 7 years from a rural village. Nordic walking exercise of 120 min per week was performed for 12 weeks. Twelve -week changes in the various factors were calculated by subtracting the baseline values from the 12 -week values. Results: Changes in sit-and-reach increased progressively with decreased changes in the MDA-LDL after the 12 -week walking exercise (r=0.312 p=0.014). Multiple linear regression analysis showed that change in the MDA-LDL (fl=0.284, p=0.021) as well as change in waist circumference (beta=0.258, p=0.036) was significantly and independently associated with change in sit-and-reach. When the data were further stratified by age, change in the MDA-LDL was significantly associated with change in sit -and -reach in women aged of 70 years. Conclusions: These results suggest that decreased change in MDA-LDL is a confounding factor for sit -and -reach after a 12 -week NW exercise in community-dwelling women. 2210-8335/Copyright (C) 2017, Asia Pacific League of Clinical Gerontology & Geriatrics. Published by Content Ed Net Taiwan Limited.