Ischemic Stroke Induces Rapid Renal Oxidative Stress and Lipometabolic Change
Juntendo Medical Journal(2020)
摘要
Objective: Stroke is associated with high risks for mortality. The bidirectional communication between ischemic brain and other organ dysfunctions is widely recognized. However, the mechanisms underlying cerebrorenal crosstalk remains unclear. Herein, we investigated the effect of ischemic stroke on the kidney using a middle cerebral artery occlusion (MCAO) model. Moreover, we explored the effects of overexpression of liver-type fatty acid binding protein (L-FABP), as antioxidant role in this disease.
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关键词
rapid renal oxidative stress,ischemic stroke,oxidative stress,lipometabolic change
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