Potassium channels in the neuronal homeostasis and neurodegenerative pathways underlying Alzheimer’s disease: An update

Mechanisms of Ageing and Development(2020)

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摘要
•Potassium (K+) channels are key regulators of cell excitability in several tissues.•A dysregulation of K+ channels is associated with Alzheimer’s disease (AD).•The role of K+ channels in AD is not completely elucidated.•Understanding their functions will be helpful for clarifying AD pathogenesis.•Modulating K+ channel expression should be useful for developing novel drugs.
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关键词
K+ channel,Alzheimer’s disease,Kir channels,KV channels,HCN channels,KCa channels
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