An inhibitor of Krüppel-like factor 5 suppresses peritoneal fibrosis in mice.

Kumiko Muta,Yuka Nakazawa,Yoko Obata,Hiro Inoue,Kenta Torigoe,Masayuki Nakazawa,Katsushige Abe,Akira Furusu,Masanobu Miyazaki,Kazuo Yamamoto,Takehiko Koji,Tomoya Nishino

NEPHROLOGY DIALYSIS TRANSPLANTATION（2021）

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摘要

These results indicate the involvement of KLF5 in the progression of experimental peritoneal fibrosis and suggest that Am80 may be potentially useful for the prevention of peritoneal fibrosis through inhibition of KLF5 expression.

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关键词

Am80,an inhibitor of KLF5,peritoneal dialysis,peritoneal fibrosis

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