Effect of a high fructose diet on metabolic parameters in carriers for hereditary fructose intolerance

•Hereditary fructose intolerance (HFI) is an inborn error of fructose metabolism.•Heterozygous carriers for HFI are considered as healthy carriers.•We assessed the impact of oral fructose on metabolic parameters in carriers for HFI.•Postprandial uric acid and insulin concentrations increased in carriers for HFI only.