Lung Injury After Neonatal Congenital Cardiac Surgery Is Mild and Modifiable by Corticosteroids

Anu K Kaskinen,Juho Keski-Nisula,Laura Martelius,Eeva Moilanen,Mari Hämäläinen,Paula Rautiainen,Sture Andersson,Olli M Pitkänen-Argillander

Journal of Cardiothoracic and Vascular Anesthesia（2021）

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摘要

•Modern open-heart surgery induces minimal lung edema in neonates.•Stress-dose corticosteroid regimen reduced radiographically assessed lung edema.•Stress-dose corticosteroid improved postoperative dynamic lung compliance.•No benefit for need of postoperative ventilator support or oxygenation was observed.•No benefit for inflammatory response in tracheal aspirate was observed.

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关键词

lung injury,infant,glucocorticoid,congenital heart defect,pulmonary injury,pulmonary edema,cardiac surgery

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