Primary platinum drug-resistant human ovarian cancer cell line FDOVL as well as preparation method and application thereof

user-5f8411ab4c775e9685ff56d3(2020)

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摘要
The invention belongs to the field of microbial animal cell lines, and particularly relates to a primary platinum drug-resistant human ovarian cancer cell line as well as an establishment method and an application thereof. The primary platinum drug-resistant human ovarian cancer cell line is established through primary culture of a primary platinum drug-resistant ovarian high-grade serous cancer secondary tumor reduction/inactivation left pelvic cavity metastatic lymph node excision specimen. The cell line is good in tumorigenicity and can be used for establishing a primary platinum drug-resistant epithelial ovarian cancer animal model. The primary platinum drug-resistant human ovarian cancer cell line can be used for occurrence, development and metastasis mechanisms of platinum drug-resistant epithelial ovarian cancer, new drug screening, drug resistance mechanisms and preclinical research.
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关键词
Metastasis,Cancer,Serous fluid,Lymph node,Cell culture,Cancer research,Drug resistance,Drug,Platinum,Medicine
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