Five-Year Adjuvant Endocrine Therapy Adherence Trajectories Among Women With Breast Cancer: A Nationwide French Study Using Administrative Data

Grégory Lailler, Victoria Memoli, Christine Le Bihan Benjamin, Marc-Karim Ben Diane, Sophie Lauzier, Julien Mancini,Philippe Jean Bousquet,Anne-Déborah Bouhnik

Clinical Breast Cancer(2021)

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摘要
•A large proportion of women are nonadherent to adjuvant endocrine therapy.•Seventy percent of women will have optimal adherence for 5 years.•Extreme age categories and switching adjuvant endocrine therapy were associated with nonadherence trajectories.•Four percent of women followed a “continuous suboptimal adherence trajectory,” previously unidentified in the literature.
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关键词
Breast cancer,Epidemiology,Group-based trajectory modeling,Hormone therapy,Medication adherence,Pharmaco-epidemiology
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