Predictive Value Of Plasma Tumor Mutation Burden (Tmb) In The Cctg Pa.7 Trial: Gemcitabine (Gem) And Nab-Paclitaxel (Nab-P) Vs. Gem, Nab-P, Durvalumab (D) And Tremelimumab (T) As First Line Therapy In Metastatic Pancreatic Ductal Adenocarcinoma (Mpdac).

JOURNAL OF CLINICAL ONCOLOGY(2021)

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摘要
411Background: PA.7 evaluated whether combining PD-L1 and CTLA-4 inhibition with GEM and Nab-P increases efficacy as first line therapy in mPDAC. High TMB is associated with immunotherapy sensitivi...
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