Application of terminal effect T cell subgroup to preparation of kit for assisting in evaluating degree of illness of aplastic anemia (AA)

user-5f8cf9244c775ec6fa691c99(2019)

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摘要
The invention discloses an application of a terminal effect T cell subgroup to preparation of a kit for assisting in evaluating the degree of illness of aplastic anemia (AA). The inventor discovers the proportion of CD8 CD45RO CD27 T cells in peripheral blood of an AA patient is obviously reduced for the first time, especially in peripheral blood of an SAA (Severe aplastic anemia) patient. The characteristic change that the proportion of CD8 CD45RO CD27 T cells in peripheral blood of the SAA patient is obviously lower than that of CD8 CD45RO CD27 T cells in the peripheral blood of an NASS ((Non-severe aplastic anemia) patient can be used as one of laboratory immunity related detection indexes for assisting in evaluating the illness degree of the AA patient, and meanwhileimportant reference data are provided for clinical selection of treatment strategies of AA patients with different illness degrees in future.
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关键词
Aplastic anemia,T cell,CD8,Immunology,Immunity,Medicine,Peripheral blood,Severe Aplastic Anemia,Treatment strategy
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