New-Onset Seizure With Possible Limbic Encephalitis In A Patient With Covid-19 Infection: A Case Report And Review

Riwaj Bhagat, Barbara Kwiecinska, Nolan Smith, Matthew Peters,Christopher Shafer,Adriana Palade,Vishwanath Sagi

JOURNAL OF INVESTIGATIVE MEDICINE HIGH IMPACT CASE REPORTS(2021)

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摘要
With the outbreak of COVID-19 (coronavirus disease 2019) as a global pandemic, various of its neurological manifestations have been reported. We report a case of a 54-year-old male with new-onset seizure who tested positive for severe acute respiratory syndrome coronavirus 2 from a nasopharyngeal swab sample. Investigative findings, which included contrast-enhancing right posterior temporal lobe T2-hyperintensity on brain magnetic resonance imaging, right-sided lateralized periodic discharges on the electroencephalogram, and elevated protein level on cerebrospinal fluid analysis, supported the diagnosis of possible encephalitis from COVID-19 infection. The findings in this case are placed in the context of the existing literature.
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关键词
COVID-19, SARS-CoV-2, encephalitis, seizure, review
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