Five-membered heterocyclic pyrazine compound, and preparation method, intermediate, composition and application thereof

Shen Jingkang,Ding Jian,Geng Meiyu,Xiong Bing,Ai Jing,Ma Yuchi,Dai Yang

user-5f8cf7e04c775ec6fa691c92（2018）

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摘要

The invention discloses a five-membered heterocyclic pyrazine compound, and a preparation method, an intermediate, a composition and application thereof. The five-membered heterocyclic pyrazine compound provided by the invention has excellent FGFR inhibition activity.

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关键词

Pyrazine,FGFR Inhibition,Combinatorial chemistry,Intermediate composition,Chemistry,Preparation method

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