NAFLD and MAFLD as emerging causes of HCC: A populational study

JHEP Reports(2021)

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摘要
•The burden of HCC arising in the context of non-alcoholic and metabolic-associated fatty liver disease (NAFLD and MAFLD) remains unclear.•We assessed all HCC cases between 1990 and 2014 in an area of western Switzerland.•We found a significant increase in overall HCC incidence in women but not in men.•The proportion of NAFLD- and MAFLD-HCC increased in both sexes, particularly in women.•Liver function of MAFLD patients was intermediate between ‘pure’ NAFLD and non-MAFLD individuals.
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关键词
Liver cancer,Hepatocellular carcinoma,Metabolic syndrome,Fatty liver,Women’s health
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